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Article

SLC29A1 polymorphism and prediction of anaemia severity in patients with chronic hepatitis C receiving triple therapy with telaprevir.

The Journal of antimicrobial chemotherapy - 1 Apr 2015

Milazzo Laura, Peri Anna Maria, Mazzali Cristina, Magni Carlo, Calvi Elisa, De Nicolò Amedeo, Clementi Emilio, Cheli Stefania, D'Avolio Antonio, Antinori Spinello, Falvella Felicia Stefania

Abstract excerpt

OBJECTIVES: The equilibrative nucleoside transporter 1 (ENT1) is the main protein involved in ribavirin cellular uptake. Polymorphisms at the SLC29A1 gene, encoding ENT1, may influence ribavirin-associated anaemia, which is observed at a higher incidence with telaprevir in combination with pegylated-IFNα and ribavirin than with pegylated-IFNα and ribavirin alone. In this study, we investigated the role of the...

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Share to Anemia
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Therapy, Combination

Share to Genotyping Techniques

Share to Hepatitis C, Chronic

Share to Interferon-alpha

Share to Oligopeptides

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Source

Identifiers

PMID: 25583751
DOI: 10.1093/jac/dku519

Genes

ITPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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