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Article

Contribution of ribavirin transporter gene polymorphism to treatment response in peginterferon plus ribavirin therapy for HCV genotype 1b patients.

Liver international : official journal of the International Association for the Study of the Liver - 1 May 2012

Tsubota Akihito, Shimada Noritomo, Yoshizawa Kai, Furihata Tomomi, Agata Rie, Yumoto Yoko, Abe Hiroshi, Ika Makiko, Namiki Yoshihisa, Chiba Kan, Fujise Kiyotaka, Tada Norio, Aizawa Yoshio

Abstract excerpt

BACKGROUND: Standard-dose ribavirin is crucial for the standard-of-care treatment of chronic hepatitis C virus (HCV) infection. Equilibrative nucleoside transporter 1 (ENT1), encoded by SLC29A1 gene, is the main transporter that imports ribavirin into human hepatocytes. AIMS: To determine whether single nucleotide polymorphisms (SNPs) at the SLC29A1 gene could influence the probability of treatment response...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22212648
DOI: 10.1111/j.1478-3231.2011.02727.x

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ITPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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