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Article

Inosine triphosphatase allele frequency and association with ribavirin-induced anaemia in Brazilian patients receiving antiviral therapy for chronic hepatitis C.

Memorias do Instituto Oswaldo Cruz - 1 Aug 2015

Delvaux Nathália, Costa Vanessa Duarte da, Costa Maristella Matos da, Villar Livia Melo, Coelho Henrique Sérgio Moraes, Esberard Eliane Bordalo Cathalá, Flores Priscila Pollo, Brandão-Mello Carlos Eduardo, Villela-Nogueira Cristiane Alves, Almeida Adilson José de, Lampe Elisabeth

Abstract excerpt

Inosine triphosphatase (ITPA) single nucleotide polymorphisms (SNPs) are strongly associated with protection against ribavirin (RBV)-induced anaemia in European, American and Asian patients; however, there is a paucity of data for Brazilian patients. The aim of this study was to evaluate the ITPA SNP (rs7270101/rs1127354) frequency in healthy and hepatitis C virus (HCV)-infected patients from Brazil and the...

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Share to Anemia
Share to Antiviral Agents
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Share to Case-Control Studies
Share to Gene Frequency
Share to Hepatitis C, Chronic
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Source

Open in PubMed Open full text

Identifiers

PMID: 26154744
DOI: 10.1590/0074-02760150104
PMCID: PMC4569827

Genes

ITPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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