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Article

Role of ITPA and SLC28A2 genes in the prediction of anaemia associated with protease inhibitor plus ribavirin and peginterferon in hepatitis C treatment.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2015

Ampuero Javier, Del Campo José Antonio, Rojas Lourdes, Calleja José Luis, Cabezas Joaquín, Lens Sabela, Crespo Javier, Forns Xavier, Andrade Raúl J, Fernández Inmaculada, Buti María, Millán Raquel, Romero-Gómez Manuel

Abstract excerpt

BACKGROUND: Anaemia is a common side-effect of ribavirin (RBV) use that overwhelms management of hepatitis C when protease inhibitors are added. AIM: To assess the pharmacogenomic impact of candidate genes SLC28A2, SLC28A3 and ITPA on anaemia in patients receiving triple therapy. METHODS: Patients (n=161) with chronic hepatitis C genotype 1 treated with telaprevir (n=95) or boceprevir (n=66) were included. Using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26071337
DOI: 10.1016/j.jcv.2015.05.010

Genes

ITPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of ITPA and SLC28A2 genes in the prediction of anaemia associated with protease inhibitor plus ribavirin and peginterferon in hepatitis C treatment.PMID 26071337Read ↗

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