Article
ITPA and SLC29A1 Genotyping for the Prediction of Ribavirin Dose Reduction in Anti-HCV Triple Therapy with Protease Inhibitors.
Pharmacology - 1 Jan 2015
Lombardi Andrea, Landonio Simona, Magni Carlo, Cheli Stefania, Mazzali Cristina, Mondelli Mario U, Rizzardini Giuliano, Clementi Emilio, Falvella Felicia Stefania
Abstract excerpt
Chronic hepatitis C is one of the most important causes of liver disease, leading to cirrhosis, hepatic decompensation and hepatocellular carcinoma. Recently some important advances in therapy have been achieved with the introduction of first wave, first generation direct acting antiviral agents (DAAs) such as boceprevir (BOC), in combination with pegylated interferon (Peg-IFN) and ribavirin (RBV). The superior...
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