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Article

Mutation screening of the Krüppel-like factor 1 gene using single-strand conformational polymorphism in a cohort of Iranian β-thalassemia patients.

Hemoglobin - 1 Jan 2015

Zaker-Kandjani Behzad, Namdar-Aligoodarzi Pegah, Azarkeivan Azita, Najmabadi Hossein, Banan Mehdi

Abstract excerpt

The Krüppel-like factor 1 (KLF1) is an essential erythroid-specific transcription factor. Mutations in the human KLF1 gene have different phenotypic effects, ranging from increased Hb F levels to the disruption of erythropoiesis. Here, we screened 227 Iranian β-thalassemia (β-thal) patients for the presence of KLF1 mutations by using the single-strand conformational polymorphism (SSCP) approach. Our aim was to...

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Source

Identifiers

PMID: 25583416
DOI: 10.3109/03630269.2014.991023

Genes

KLF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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