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Article

KLF1 gene mutations in Chinese adults with increased fetal hemoglobin.

Hemoglobin - 1 Jan 2013

Wang Ting, He Yi, Zhou Jian-Ying, Xie Xing-Mei, Li Jian, Li Ru, Liao Can, Li Dong-Zhi

Abstract excerpt

We investigated the Krüppel-like factor 1 (KLF1) gene mutations in Chinese adults with increased Hb F levels (>1.5%) referred to our laboratory for thalassemia screening. Functionally effective KLF1 mutations were identified in five out of 140 samples with an elevated Hb F (1.9-11.4%). Only two different KLF1 mutations were detected. Functional KLF1 mutations were not identified in the matched cohort of 110...

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Source

Identifiers

PMID: 23806141
DOI: 10.3109/03630269.2013.805304

Genes

KLF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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