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Article

Exploratory study on association of single-nucleotide polymorphisms with hydromorphone analgesia in ED.

The American journal of emergency medicine - 1 Mar 2015

Xia Shujun, Persaud Shaun, Birnbaum Adrienne

Abstract excerpt

OBJECTIVES: The objective of this study is to provide information on distribution of important single-nucleotide polymorphisms (SNPs) and evaluate their associations with clinical response to intravenous hydromorphone in emergency department. METHODS: A prospective exploratory study was performed. A convenience sample of adult emergency department patients with acute pain deemed to require intravenous opioids...

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Topics

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Share to Administration, Intravenous
Share to Analgesics, Opioid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B

Share to Emergency Service, Hospital

Share to Glucuronosyltransferase

Share to Pain Measurement

Share to Patient Satisfaction

Share to Receptors, Opioid, mu

Source

Open in PubMed Open full text

Identifiers

PMID: 25576257
DOI: 10.1016/j.ajem.2014.12.008
PMCID: PMC4385400

Genes

OPRM1
ABCB1
COMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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