Article
Disputed rpoB mutations can frequently cause important rifampicin resistance among new tuberculosis patients.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Feb 2015
Van Deun A, Aung K J M, Hossain A, de Rijk P, Gumusboga M, Rigouts L, de Jong B C
Abstract excerpt
SETTING: Greater Mymensingh area, Bangladesh. OBJECTIVES: To document among new tuberculosis (TB) patients the proportions and treatment outcomes of silent, non-disputed and disputed (generally missed by rapid drug susceptibility testing [DST]) rpoB mutations, and their detection by commercial molecular assays. DESIGN: Retrospective analysis of rpoB sequences from randomly selected ethanol-preserved diagnostic...
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