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Discordances between molecular assays for rifampicin resistance in Mycobacterium tuberculosis : frequency, mechanisms and clinical impact

20 Dec 2019

Abstract excerpt

BACKGROUND: Molecular assays are endorsed for detection and confirmation of rifampicin-resistant TB. The frequency, causal mechanisms and impact of discordant results between molecular tests are not well understood. METHODS: The prevalence of discordant results was determined by pairwise comparison of molecular test results in a cohort of 749 rifampicin-resistant TB patients in three South African provinces....

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PMID: 32016320
DOI: 10.1093/jac/dkz564

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