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Article

Disputed rpoB Mutations in Mycobacterium tuberculosis and Tuberculosis Treatment Outcomes.

Antimicrobial agents and chemotherapy - 17 Jun 2021

Lin Wan-Hsuan, Lee Wei-Ting, Tsai Hsing-Yuan, Jou Ruwen

Abstract excerpt

Discordant results between genotypic drug susceptibility testing (gDST) and phenotypic DST (pDST) for Mycobacterium tuberculosis isolates with disputed (discordance between gDST and pDST results) mutations affect rifampin (RIF)-resistant (RR) and multidrug-resistant (MDR) tuberculosis (TB) treatments due to a lack of practical clinical guidelines. To investigate the role of disputed rpoB mutations in M....

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Identifiers

PMID: 33846134
DOI: 10.1128/AAC.01573-20
PMCID: PMC8218645

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