Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rifampin Drug Resistance Tests for Tuberculosis: Challenging the Gold Standard

13 Jun 2013

Abstract excerpt

The rapid diagnosis of rifampin resistance is hampered by a reported insufficient specificity of molecular techniques for detection of rpoB mutations. Our objective for this study was to document the prevalence and prognostic value of rpoB mutations with unclear phenotypic resistance. The study design entailed sequencing directly from sputum of first failure or relapse patients without phenotypic selection and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mycobacterium research and diagnosis
Share to Pneumocystis jirovecii pneumonia detection and treatment
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23761144
DOI: 10.1128/jcm.00553-13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rifampin Drug Resistance Tests for Tuberculosis: Challenging the Gold StandardPMID 23761144Read ↗

Disputed rpoB mutations can frequently cause important rifampicin resistance among new tuberculosis patients.Semantic proximity Read ↗

Disputed rpoB Mutations in Mycobacterium tuberculosis and Tuberculosis Treatment Outcomes.Semantic proximity Read ↗

Occurrence of disputed rpoB mutations among Mycobacterium tuberculosis isolates phenotypically susceptible to rifampicin in a country with a low incidence of multidrug-resistant tuberculosisSemantic proximity Read ↗

Rifampin Resistance Missed in Automated Liquid Culture System for Mycobacterium tuberculosis Isolates with Specific <i>rpoB</i> MutationsSemantic proximity Read ↗

Unveiling the complexity of rifampicin drug susceptibility testing in Mycobacterium tuberculosis: comparative analysis with next-generation sequencing.Semantic proximity Read ↗

Role of Disputed Mutations in the rpoB Gene in Interpretation of Automated Liquid MGIT Culture Results for Rifampin Susceptibility Testing of Mycobacterium tuberculosis.Semantic proximity Read ↗

Phenotype versus genotype discordant rifampicin susceptibility testing in tuberculosis: implications for a diagnostic accuracy.Semantic proximity Read ↗

Are WHO approved nucleic acid amplification tests causing large-scale "false identification" of rifampicin-resistant tuberculosis?: Programmatic experience from south india.Semantic proximity Read ↗

rpoB Mutations Causing Discordant Rifampicin Susceptibility in Mycobacterium tuberculosis: Retrospective Analysis of Prevalence, Phenotypic, Genotypic, and Treatment OutcomesSemantic proximity Read ↗

Beyond Hotspot Mutations: Diagnostic Relevance of High Frequency, Low Frequency, and Disputed rpoB Variants in Rifampicin-Resistant Mycobacterium tuberculosis.Semantic proximity Read ↗

Consequences of rpoB mutations missed by the GenoType MTBDRplus assay in a programmatic setting in South AfricaSemantic proximity Read ↗

Discordance across Phenotypic and Molecular Methods for Drug Susceptibility Testing of Drug-Resistant Mycobacterium tuberculosis Isolates in a Low TB Incidence Country.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.