Article
Sex differences in deleterious mutational effects in Drosophila melanogaster: combining quantitative and population genetic insights.
Genetics - 5 Nov 2021
Ruzicka Filip, Connallon Tim, Reuter Max
Abstract excerpt
Fitness effects of deleterious mutations can differ between females and males due to: (i) sex differences in the strength of purifying selection; and (ii) sex differences in ploidy. Although sex differences in fitness effects have important broader implications (e.g., for the evolution of sex and lifespan), few studies have quantified their scope. Those that have belong to one of two distinct empirical...
Topics
- Alleles
- Animals
- Chromosomes, Insect
- Drosophila melanogaster
- Evolution, Molecular
- Female
- Gene Frequency
- Genes, Insect
- Genetic Fitness
- Genome-Wide Association Study
- Linear Models
- Male
- Models, Genetic
- Multifactorial Inheritance
- Polymorphism, Genetic