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Article

Epigenetic Heterogeneity in HIV-1 Latency Establishment

9 Jan 2015

Abstract excerpt

Despite prolonged antiretroviral therapy, HIV-1 persists as transcriptionally inactive proviruses. The HIV-1 latency remains a principal obstacle in curing AIDS. It is important to understand mechanisms by which HIV-1 latency is established to make the latent reservoir smaller. We present a molecular characterization of distinct populations at an early phase of infection. We developed an original dual-color...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25572573
DOI: 10.1038/srep07701

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