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Article

HIV latency: experimental systems and molecular models

28 Feb 2012

Abstract excerpt

Highly active antiretroviral therapy (HAART) has shown great efficacy in increasing the survival of HIV infected individuals. However, HAART does not lead to the full eradication of infection and therefore has to be continued for life. HIV persists in a transcriptionally inactive form in resting T cells in HAART-treated patients and can be reactivated following T-cell activation. These latently infected cells...

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PMID: 22372374
DOI: 10.1111/j.1574-6976.2012.00335.x

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