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Article

The sounds of silencing: dynamic epigenetic control of HIV latency

12 Mar 2024

Abstract excerpt

PURPOSE OF REVIEW: This review highlights advances in understanding the epigenetic control mechanisms that regulate HIV-1 latency mechanisms in T-cells and microglial cells and describes the potential of current therapeutic approaches targeting the epigenetic machinery to eliminate or block the HIV-1 latent reservoir. RECENT FINDINGS: Large-scale unbiased CRISPR-Cas9 library-based screenings, coupled with...

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PMID: 38547337
DOI: 10.1097/coh.0000000000000850

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