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Epigenetic Mechanisms of HIV-1 Persistence

17 May 2021

Abstract excerpt

Eradicating HIV-1 in infected individuals will not be possible without addressing the persistence of the virus in its multiple reservoirs. In this context, the molecular characterization of HIV-1 persistence is key for the development of rationalized therapeutic interventions. HIV-1 gene expression relies on the redundant and cooperative recruitment of cellular epigenetic machineries to cis-regulatory proviral...

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PMID: 34067608
DOI: 10.3390/vaccines9050514

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