Article
HIV-1 Latency and Latency Reversal: Does Subtype Matter?
Viruses - 28 Nov 2019
Sarabia Indra, Bosque Alberto
Abstract excerpt
Cells that are latently infected with HIV-1 preclude an HIV-1 cure, as antiretroviral therapy does not target this latent population. HIV-1 is highly genetically diverse, with over 10 subtypes and numerous recombinant forms circulating worldwide. In spite of this vast diversity, much of our understanding of latency and latency reversal is largely based on subtype B viruses. As such, most of the development of...
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