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Article

Human Urine-Derived Renal Progenitors for Personalized Modeling of Genetic Kidney Disorders

8 Jan 2015

Abstract excerpt

The critical role of genetic and epigenetic factors in the pathogenesis of kidney disorders is gradually becoming clear, and the need for disease models that recapitulate human kidney disorders in a personalized manner is paramount. In this study, we describe a method to select and amplify renal progenitor cultures from the urine of patients with kidney disorders. Urine-derived human renal progenitors exhibited...

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PMID: 25568173
DOI: 10.1681/asn.2014010057

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