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Urine-Derived Epithelial Cells as Models for Genetic Kidney Diseases

6 Jun 2021

Abstract excerpt

Epithelial cells exfoliated in human urine can include cells anywhere from the urinary tract and kidneys; however, podocytes and proximal tubular epithelial cells (PTECs) are by far the most relevant cell types for the study of genetic kidney diseases. When maintained in vitro, they have been proven extremely valuable for discovering disease mechanisms and for the development of new therapies. Furthermore,...

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PMID: 34204173
DOI: 10.3390/cells10061413

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