Unveiling Spontaneous Renal Tubule-Like Structures from Human Adult Renal Progenitor Cell Spheroids Derived from Urine

Abstract excerpt

<title>Abstract</title> <p>The rapidly developing field of renal spheroids and organoids has emerged as a valuable tool for modeling nephrotoxicity, kidney disorders, and kidney development. However, existing studies have relied on intricate and sophisticated differentiation protocols to generate organoids and tubuloids, necessitating the external administration of multiple growth factors within precise timeframe...

Topics

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• Cell Lineage
• CRISPR-Cas Systems
• Drug Discovery
• Gene Editing
• High-Throughput Screening Assays
• Induced Pluripotent Stem Cells
• Organoids
• Renal and related cancers

Identifiers and source

Literature Corpus work

f1a4735f-2059-513d-b12a-56e8e6d03749

DOI

10.21203/rs.3.rs-4459581/v2