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Article

Interest of genotyping and phenotyping of drug-metabolizing enzymes for the interpretation of biological monitoring of exposure to styrene.

Pharmacogenetics - 1 Dec 2002

Haufroid Vincent, Jakubowski Marek, Janasik Beata, Ligocka Danuta, Buchet Jean-Pierre, Bergamaschi Enrico, Manini Paola, Mutti Antonio, Ghittori Sergio, Arand Michael, Hangen Nina, Oesch Franz, Hirvonen Ari, Lison Dominique

Abstract excerpt

In the field of occupational and/or environmental toxicology, the measurement of specific metabolites in urine may serve to assess exposure to the parent compounds (biological monitoring of exposure). Styrene is one of the chemicals for which biological monitoring programs have been validated and implemented in environmental and occupational medicine. However, inter-individual differences in the urinary excretion...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12464798
DOI: 10.1097/00008571-200212000-00003

Genes

GSTM1
EPHX1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interest of genotyping and phenotyping of drug-metabolizing enzymes for the interpretation of biological monitoring of exposure to styrene.PMID 12464798Read ↗

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Use of the CYP2E1 genotype and phenotype for the biological monitoring of occupational exposure to styrene.Semantic proximity Read ↗

Occupational exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 and GSTP1.Semantic proximity Read ↗

Influence of genetic polymorphisms of styrene-metabolizing enzymes and smoking habits on levels of urinary metabolites after occupational exposure to styrene.Semantic proximity Read ↗

GSTM1 polymorphism and styrene metabolism: insights from an acute accidental exposure.Semantic proximity Read ↗

DNA damage and susceptibility assessment in industrial workers exposed to styrene.Semantic proximity Read ↗

Cytogenetic biomarkers, urinary metabolites and metabolic gene polymorphisms in workers exposed to styrene.Semantic proximity Read ↗

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