Article
Association between IRS-1 Gly972Arg polymorphism and colorectal cancer risk.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2014
Li Peng, Wang Lingjun, Liu Lihua, Jiang Hong, Ma Chong, Hao Tao
Abstract excerpt
In order to make a comprehensive assessment of the potential association between one genetic variant in the insulin receptor substrate 1 (IRS-1) gene, rs1801278, and colorectal cancer (CRC) risk, we conducted a meta-analysis of four epidemiological studies, which included 3,708 CRC cases and 4,176 controls. The data showed that rs1801278 polymorphism was not associated with increased CRC risk in the overall...
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