Article
Characterization and prognostic significance of mitochondrial DNA variations in acute myeloid leukemia.
European journal of haematology - 1 May 2013
Silkjaer Trine, Nørgaard Jan Maxwell, Aggerholm Anni, Ebbesen Lene Hyldahl, Kjeldsen Eigil, Hokland Peter, Nyvold Charlotte Guldborg
Abstract excerpt
Recent studies have suggested that mutations in the mitochondrial genome (mtDNA) may play a role in the development and response to treatment for human cancer. The aim of this study was to investigate whether mtDNA variations have any prognostic relevance, to clarify the spectra of mtDNA variatio...
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