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Article

SLCO1B1 and MTRR gene variants in pediatric acute lymphoblastic leukemia: a study on Egyptian children.

Molecular biology reports - 22 Jul 2026

Mahdi Ali Nabeel, Elsaid Afaf M, Mohammed Maha Abdelmoneim, Madkour Mai M, Abdel-Aziz A F

Abstract excerpt

BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common malignancy in pediatric populations and affects white blood cells. The solute carrier organic anion transporter family member 1B1 (SLCO1B1) gene encodes the organic anion transporting polypeptide 1B1 (OATP1B1), a transporter involved in drug metabolism, whereas methionine synthase reductase (MTRR) plays an essential role in DNA synthesis and...

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Identifiers

PMID: 42484704
DOI: 10.1007/s11033-026-12358-w

Genes

MTRR
SLCO1B1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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