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Article

The V gene repertoires of classical and atypical memory B cells in malaria-susceptible West African children.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2015

Zinöcker Severin, Schindler Christine E, Skinner Jeff, Rogosch Tobias, Waisberg Michael, Schickel Jean-Nicolas, Meffre Eric, Kayentao Kassoum, Ongoïba Aïssata, Traoré Boubacar, Pierce Susan K

Abstract excerpt

Immunity to Plasmodium falciparum malaria is naturally acquired in individuals living in malaria-endemic areas of Africa. Abs play a key role in mediating this immunity; however, the acquisition of the components of Ab immunity, long-lived plasma cells and memory B cells (MBCs), is remarkably inefficient, requiring years of malaria exposure. Although long-lived classical MBCs...

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Share to Africa, Western
Share to Antigens, Protozoan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complementarity Determining Regions

Share to Gene Rearrangement, B-Lymphocyte

Share to Immunoglobulin Light Chains

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Share to Somatic Hypermutation, Immunoglobulin

Source

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Identifiers

PMID: 25556245
DOI: 10.4049/jimmunol.1402168
PMCID: PMC4297690

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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