Article
Suppression of circulating IgD+CD27+ memory B cells in infants living in a malaria-endemic region of Kenya.
Malaria journal - 13 Dec 2011
Asito Amolo S, Piriou Erwan, Jura Walter G Z O, Ouma Collins, Odada Peter S, Ogola Sidney, Fiore Nancy, Rochford Rosemary
Abstract excerpt
BACKGROUND: Plasmodium falciparum infection leads to alterations in B cell subset distribution. During infancy, development of peripheral B cell subsets is also occurring. However, it is unknown if infants living a malaria endemic region have alterations in B cell subsets that is independent of an age effect. METHODS: To evaluate the impact of exposure to P. falciparum on B cell development in infants, flow...
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