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Article

Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis.

Neurobiology of disease - 1 Mar 2015

Ehret Fanny, Vogler Steffen, Pojar Sherin, Elliott David A, Bradke Frank, Steiner Barbara, Kempermann Gerd

Abstract excerpt

Could impaired adult hippocampal neurogenesis be a relevant mechanism underlying CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy)? Memory symptoms in CADASIL, the most common hereditary form of vascular dementia, are usually thought to be primarily due to vascular degeneration and white matter lacunes. Since adult hippocampal neurogenesis, a process essential...

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Source

Identifiers

PMID: 25555543
DOI: 10.1016/j.nbd.2014.12.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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