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Article

Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associations

1 Dec 2014

Abstract excerpt

BACKGROUND: Previous studies investigating a genetic basis for idiopathic pulmonary fibrosis (IPF) have focused on resequencing single genes in IPF kindreds or cohorts to determine the genetic contributions to IPF. None has investigated interactions among the candidate genes. OBJECTIVE: To compare the frequencies and interactions of mutations in six IPF-associated genes in a cohort of 132 individuals with IPF...

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PMID: 25553246
DOI: 10.1136/bmjresp-2014-000057

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