Whole-exome sequencing identifies susceptibility genes and pathways for idiopathic pulmonary fibrosis in the Chinese population.

doi:10.1038/s41598-020-80944-4

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Whole-exome sequencing identifies susceptibility genes and pathways for idiopathic pulmonary fibrosis in the Chinese population.

Scientific reports - 14 Jan 2021

Fang Chuling, Huang Hui, Feng Yujia, Zhang Qian, Wang Na, Jing Xiaoyan, Guo Jian, Ferianc Martin, Xu Zuojun

Abstract excerpt

Genetic factors play a role in the risk of idiopathic pulmonary fibrosis (IPF). Specifically, MUC5B rs35705950 non-risk alleles and immunologic aberrations were associated with the IPF's progression. However, rare genetic variants have not been systematically investigated in Chinese IPF patients. In this study, we aimed to improve understanding of the genetic architecture of IPF in the Chinese population and to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to China

Share to Exome Sequencing

Share to Genome-Wide Association Study

Share to Idiopathic Pulmonary Fibrosis

Share to Mucin-5B

Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 33446833
DOI: 10.1038/s41598-020-80944-4
PMCID: PMC7809470

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole-exome sequencing identifies susceptibility genes and pathways for idiopathic pulmonary fibrosis in the Chinese population.PMID 33446833Read ↗

IDIOPATHIC PULMONARY FIBROSIS IS A COMPLEX GENETIC DISORDER.Semantic proximity Read ↗

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.Semantic proximity Read ↗

Genetic Risk Factors for Idiopathic Pulmonary Fibrosis: Insights into ImmunopathogenesisSemantic proximity Read ↗

Common single nucleotide polymorphisms associated with idiopathic pulmonary fibrosis: a systematic review.Semantic proximity Read ↗

Mapping the genetic architecture of idiopathic pulmonary fibrosis: Meta-analysis and epidemiological evidence of case-control studies.Semantic proximity Read ↗

Genome-wide association study of Idiopathic Pulmonary Fibrosis susceptibility using clinically-curated European-ancestry datasetsSemantic proximity Read ↗

Genetics in Idiopathic Pulmonary Fibrosis Pathogenesis, Prognosis, and TreatmentSemantic proximity Read ↗

Genome-wide association study of idiopathic pulmonary fibrosis susceptibility using clinically curated European ancestry datasetsSemantic proximity Read ↗

Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study.Semantic proximity Read ↗

Integrative Analyses Reveal Novel Disease-associated Loci and Genes for Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Polygenic Risk and Rare Variants in Endotypes of Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.