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Article

Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis

29 Apr 2019

Abstract excerpt

Abstract Rationale Several common and rare genetic variants have been associated with idiopathic pulmonary fibrosis, a progressive fibrotic condition that is localized to the lung. Objectives To develop an integrated understanding of the rare and common variants located in multiple loci that have been reported to contribute to the risk of disease. Methods We performed deep targeted resequencing (3.69 Mb of DNA)...

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PMID: 31034279
DOI: 10.1164/rccm.201810-1891oc

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