Association Between Single Nucleotide Polymorphisms and Disease Susceptibility, Survival, and Acute Exacerbation in Idiopathic Pulmonary Fibrosis.

doi:10.1111/resp.70120

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Article

Association Between Single Nucleotide Polymorphisms and Disease Susceptibility, Survival, and Acute Exacerbation in Idiopathic Pulmonary Fibrosis.

Respirology (Carlton, Vic.) - 1 Jan 2026

Tsubouchi Kazuya, Yanagihara Toyoshi, Kiyomi Fumiaki, Yamamoto Yuzo, Arimura-Omori Masako, Hamada Naoki, Ichiki Katsuyuki, Takata Shohei, Ishii Hiroshi, Kitasato Yasuhiko, Okamoto Masaki, Kawakami Satoru, Yatera Kazuhiro, Kawasaki Masayuki, Fujita Masaki, Tokunaga Shoji, Kiyohara Chikako, Nakanishi Yoichi, Okamoto Isamu

Abstract excerpt

BACKGROUND AND OBJECTIVE: Genetic polymorphisms have been associated with susceptibility to interstitial lung diseases including idiopathic pulmonary fibrosis (IPF). We have now examined the relation between single nucleotide polymorphisms (SNPs) and clinical course, including acute exacerbation (AE), in addition to disease susceptibility for IPF and unclassifiable idiopathic interstitial pneumonias (IIPs)....

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Identifiers

PMID: 40887773
DOI: 10.1111/resp.70120
PMCID: PMC12783960

Genes

MUC5B
TERT
AKAP13
DSP

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