Genetics in Idiopathic Pulmonary Fibrosis Pathogenesis, Prognosis, and Treatment

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial pneumonia (IIP), is characterized by irreversible scarring of the lung parenchyma and progressive decline in lung function leading to eventual respiratory failure. The prognosis of IPF is poor with a median survival of three to five years after diagnosis and no curative medical therapies. Though the pathogenesis of IPF is not...

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