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Article

Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology.

Haematologica - 1 Apr 2015

Ishikawa Yuichi, Maeda Manami, Pasham Mithun, Aguet Francois, Tacheva-Grigorova Silvia K, Masuda Takeshi, Yi Hai, Lee Sung-Uk, Xu Jian, Teruya-Feldstein Julie, Ericsson Maria, Mullally Ann, Heuser John, Kirchhausen Tom, Maeda Takahiro

Abstract excerpt

Clathrin-dependent endocytosis is an essential cellular process shared by all cell types. Despite this, precisely how endocytosis is regulated in a cell-type-specific manner and how this key pathway functions physiologically or pathophysiologically remain largely unknown. PICALM, which encodes the clathrin adaptor protein PICALM, was originally identified as a component of the CALM/AF10 leukemia oncogene. Here we...

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Source

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Identifiers

PMID: 25552701
DOI: 10.3324/haematol.2014.119537
PMCID: PMC4380716

Genes

PICALM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology.PMID 25552701Read ↗

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