Article
Uncoupling the functions of CALM in VAMP sorting and clathrin-coated pit formation.
PloS one - 1 Jan 2013
Sahlender Daniela A, Kozik Patrycja, Miller Sharon E, Peden Andrew A, Robinson Margaret S
Abstract excerpt
CALM (clathrin assembly lymphoid myeloid leukemia protein) is a cargo-selective adaptor for the post-Golgi R-SNAREs VAMPs 2, 3, and 8, and it also regulates the size of clathrin-coated pits and vesicles at the plasma membrane. The present study has two objectives: to determine whether CALM can sort additional VAMPs, and to investigate whether VAMP sorting contributes to CALM-dependent vesicle size regulation....
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