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Article

A mutant Escherichia coli that attaches peptidoglycan to lipopolysaccharide and displays cell wall on its surface.

eLife - 31 Dec 2014

Grabowicz Marcin, Andres Dorothee, Lebar Matthew D, Malojčić Goran, Kahne Daniel, Silhavy Thomas J

Abstract excerpt

The lipopolysaccharide (LPS) forms the surface-exposed leaflet of the outer membrane (OM) of Gram-negative bacteria, an organelle that shields the underlying peptidoglycan (PG) cell wall. Both LPS and PG are essential cell envelope components that are synthesized independently and assembled by dedicated transenvelope multiprotein complexes. We have identified a point-mutation in the gene for O-antigen ligase...

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Source

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Identifiers

PMID: 25551294
DOI: 10.7554/eLife.05334
PMCID: PMC4296511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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