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Article

Determinants of plasma renin activity: role of a human renin gene variant as a genetic factor.

Medicine - 1 Dec 2014

Konoshita Tadashi, Nakaya Takahiro, Sakai Ai, Yamada Mika, Ichikawa Mai, Sato Satsuki, Imagawa Michiko, Fujii Miki, Yamamoto Katsushi, Makino Yasukazu, Arakawa Kenichiro, Suzuki Jinya, Ishizuka Tamotsu

Abstract excerpt

The plasma renin activity (PRA) is affected by a number of environmental factors. However, significant heritability has been shown for the activity. A hypothesis that a candidate regulatory single-nucleotide polymorphism, C-5312T, of human renin gene should have a significant effect on PRA was elucidated and updating of independent determinants of PRA was attempted. Cross sectional study. Outpatient study. We...

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Identifiers

PMID: 25546694
DOI: 10.1097/MD.0000000000000354
PMCID: PMC4602612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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