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Article

Soluble macrophage biomarkers indicate inflammatory phenotypes in patients with knee osteoarthritis.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Apr 2015

Daghestani Hikmat N, Pieper Carl F, Kraus Virginia B

Abstract excerpt

OBJECTIVE: To evaluate the ability of the macrophage markers CD163 and CD14 to predict different osteoarthritis (OA) phenotypes defined by severity of joint inflammation, radiographic features and progression, and joint pain. METHODS: We evaluated 2 different cohorts totaling 184 patients with radiographic knee OA. These included 25 patients from a cross-sectional imaging study for whom there were data on...

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Share to Antigens, Differentiation, Myelomonocytic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25544994
DOI: 10.1002/art.39006
PMCID: PMC4441094

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