Article
Association of MRI-based knee osteoarthritis structural phenotypes with short-term structural progression and subsequent total knee replacement.
Journal of orthopaedic surgery and research - 28 Oct 2024
Liu Yukang, Xing Zikai, Wu Baoer, Chen Ning, Wu Tianxing, Cai Zhuojian, Guo Donghong, Tao Gaochenzi, Xie Zikun, Wu Chengkai, Cao Peihua, Wang Xiaoshuai, Li Jia
Abstract excerpt
BACKGROUND: The failure of disease-modifying osteoarthritis drugs (DMOADs) trials lies mainly in the heterogeneity of the disease, which calls for a more precise population with specific progression and outcomes. This study aimed to determine whether and which MRI-based structural phenotype of knee osteoarthritis (KOA) is associated with short-term structural progression and subsequent total knee replacement...
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