Article

The Combination of an Inflammatory Peripheral Blood Gene Expression and Imaging Biomarkers Enhance Prediction of Radiographic Progression in Knee Osteoarthritis.

2020-08-17

Abstract excerpt

<title>Abstract</title> <p>Objective. Predictive biomarkers of progression in knee osteoarthritis are sought to enable clinical trials of structure modifying drugs. A peripheral blood leukocyte (PBL) inflammatory gene signature, MRI-based bone marrow lesions (BML) and meniscus extrusion scores), meniscal lesions, and osteophytes on x-ray each have been shown separately to predict radiographic joint space narrowin...

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Literature Corpus work: 0bc46e2a-43e0-50f5-a093-422a64fea993
DOI: 10.21203/rs.2.23422/v3

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