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Article

Polymorphisms within Toll-like receptors are associated with systemic lupus erythematosus in a cohort of Danish females.

Rheumatology (Oxford, England) - 1 Jan 2014

Laska Magdalena Janina, Troldborg Anne, Hansen Bettina, Stengaard-Pedersen Kristian, Junker Peter, Nexø Bjørn Andersen, Voss Anne

Abstract excerpt

OBJECTIVES: Toll-like receptors (TLRs) are pattern-associated receptors in innate immunity that may be involved in the recognition of self-antigens and the production of pathogenic autoantibodies. This study was undertaken to examine whether polymorphisms of TLR genes are associated with SLE and to determine the expression of various TLRs in peripheral blood mononuclear cells (PBMCs) of patients with SLE....

Read the complete abstract on PubMed

Topics

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Share to Adolescent
Share to Immunity, Innate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lupus Erythematosus, Systemic

Share to Polymorphism, Genetic

Share to Real-Time Polymerase Chain Reaction

Share to Toll-Like Receptors

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Source

Identifiers

PMID: 24064706
DOI: 10.1093/rheumatology/ket316

Genes

TLR8
TLR3
TLR9
TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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