Article
Role of innate immune receptors TLR4 and TLR2 polymorphisms in systemic lupus erythematosus susceptibility.
Annals of human genetics - 1 May 2022
Elloumi Nesrine, Tahri Safa, Fakhfakh Raouia, Abida Olfa, Mahfoudh Nadia, Hachicha Hend, Marzouk Sameh, Bahloul Zouhir, Masmoudi Hatem
Abstract excerpt
AIM: Through their recognition of various bacterial cell wall components, TLR2 and TLR4 participate in the innate response and modulate the activation of adaptive immunity. Therefore, the genetic background of these receptors might play a crucial role in autoimmune diseases such as systemic lupus erythematosus (SLE). In this study, we investigated the possible association between polymorphisms within TLR2 and...
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