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Article

Genetic variations of Toll-like receptor 9 predispose to systemic lupus erythematosus in Japanese population.

Annals of the rheumatic diseases - 1 Jul 2007

Tao Kayoko, Fujii Mutsuko, Tsukumo Shin-ichi, Maekawa Yoichi, Kishihara Kenji, Kimoto Yasutaka, Horiuchi Takahiko, Hisaeda Hajime, Akira Shizuo, Kagami Shoji, Yasutomo Koji

Abstract excerpt

BACKGROUND: Systemic lupus erythematosus (SLE) is characterised by dysregulation of autoreactive lymphocytes and antigen-presenting cells. Signalling through Toll-like receptor 9 (TLR9), a mediator of innate immune responses, has a role in activation of dendritic cells and autoreactive B cells. O...

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Identifiers

PMID: 17344245
DOI: 10.1136/ard.2006.065961
PMCID: PMC1955115

Genes

TLR9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17344245-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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