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Article

Complete effect-profile assessment in association studies with multiple genetic and multiple environmental factors.

Genetic epidemiology - 1 Feb 2015

Wang Zhi, Maity Arnab, Luo Yiwen, Neely Megan L, Tzeng Jung-Ying

Abstract excerpt

Studying complex diseases in the post genome-wide association studies (GWAS) era has led to developing methods that consider factor-sets rather than individual genetic/environmental factors (i.e., Multi-G-Multi-E studies), and mining for potential gene-environment (G×E) interactions has proven to be an invaluable aid in both discovery and deciphering underlying biological mechanisms. Current approaches for...

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PMID: 25538034
DOI: 10.1002/gepi.21877
PMCID: PMC4314365

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