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Article

Association of SIX1-SIX6 polymorphisms with peripapillary retinal nerve fibre layer thickness in children.

The British journal of ophthalmology - 1 Aug 2023

Lu Shi Yao, Zhang Xiu Juan, Wang Yu Meng, Yuan Nan, Kam Ka Wai, Chan Poemen P, Tam Pancy Os, Yip Wilson Wk, Young Alvin L, Tham Clement C, Pang Chi Pui, Yam Jason C, Chen Li Jia

Abstract excerpt

PURPOSE: Association of SIX1-SIX6 variants with peripapillary retinal nerve fibre layer (p-RNFL) thickness had been reported in adults. This study aimed to investigate these associations in children, with further explorations by spatial, age and sex stratifications. METHODS: 2878 school children aged between 6 and 9 years were enrolled from the Hong Kong Children Eye Study. Three single-nucleotide polymorphisms...

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Identifiers

PMID: 35017159
DOI: 10.1136/bjophthalmol-2021-319756

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