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Article

Association of three single nucleotide polymorphisms at the SIX1-SIX6 locus with primary open angle glaucoma in the Chinese population.

Science China. Life sciences - 1 Jul 2016

Sang Jinghong, Jia Liyun, Zhao Bowen, Wang Huaizhou, Zhang Nihong, Wang Ningli

Abstract excerpt

This study investigated the genetic association of three single nucleotide polymorphisms (SNPs; rs10483727, rs33912345, and rs146737847) at the SIX1-SIX6 locus with primary open angle glaucoma (POAG) in the Chinese population. A total of 866 subjects with POAG (685 high-tension glaucoma (HTG) and 181 normal-tension glaucoma (NTG)) and 266 control individuals were included. Significant genetic association was...

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Source

Identifiers

PMID: 27260188
DOI: 10.1007/s11427-016-5073-y

Genes

SIX6
SIX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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