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Article

Genetic Spectrum and Genotype-Phenotype Correlations in a Chinese Cohort With Nanophthalmos With Secondary Angle-Closure Glaucoma.

Investigative ophthalmology & visual science - 2 Jun 2025

Yu Xiaowei, Zhao Hanxue, Gao Yan, Zhou Tao, Deng Lin, Zhang Miao, Zhong Hongyu, Mei Feng, Li Zhijun, Sun Longyan, Zhang Tianrui, Shi Yan, Fan Zhigang

Abstract excerpt

Purpose: The purpose of this study was to explore the genetic and clinical features of nanophthalmos with secondary angle-closure glaucoma (NSACG) in a Chinese cohort. This was a prospective cross-sectional study of 157 eyes from 88 Chinese patients with NSACG. Methods: The participants underwent ocular and systemic examinations and whole-exome sequencing. The main outcome measures were pathogenic genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40459495
DOI: 10.1167/iovs.66.6.9
PMCID: PMC12136104

Genes

AR
ACD
MFRP
PRSS56
TMEM98

Provenance

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