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Article

Genetic investigation into the endophenotypic status of central corneal thickness and optic disc parameters in relation to open-angle glaucoma.

American journal of ophthalmology - 1 Nov 2012

Dimasi David P, Burdon Kathryn P, Hewitt Alex W, Fitzgerald Jude, Wang Jie Jin, Healey Paul R, Mitchell Paul, Mackey David A, Craig Jamie E

Abstract excerpt

PURPOSE: To ascertain if single nucleotide polymorphisms (SNPs) involved in the determination of central corneal thickness, optic disc area, and vertical cup-to-disc ratio (VCDR) also are associated with open-angle glaucoma (OAG). DESIGN: Retrospective case-control genetic association study. METHODS: A total of 16 SNPs associated with central corneal thickness, optic disc area, and VCDR were genotyped in 876 OAG...

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Identifiers

PMID: 22840486
DOI: 10.1016/j.ajo.2012.04.023

Genes

SIX1

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