Article
A genome-wide transgenic resource for conditional expression of Drosophila microRNAs.
Development (Cambridge, England) - 1 Aug 2012
Bejarano Fernando, Bortolamiol-Becet Diane, Dai Qi, Sun Kailiang, Saj Abil, Chou Yu-Ting, Raleigh David R, Kim Kevin, Ni Jian-Quan, Duan Hong, Yang Jr-Shiuan, Fulga Tudor A, Van Vactor David, Perrimon Norbert, Lai Eric C
Abstract excerpt
microRNAs (miRNAs) are endogenous short RNAs that mediate vast networks of post-transcriptional gene regulation. Although computational searches and experimental profiling provide evidence for hundreds of functional targets for individual miRNAs, such data rarely provide clear insight into the phenotypic consequences of manipulating miRNAs in vivo. We describe a genome-wide collection of 165 Drosophila miRNA...
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