[Colorectal serrated lesions: current insight on their role in colorectal carcinogenesis].

Abstract excerpt

The classification of colorectal cancer precursor lesions has become more accurate after the discovery of serrated polyps. These are characterized by saw-tooth-like epithelial growth pattern, and are the most significant group of colorectal cancer precursors after conventional adenomas. While conventional adenomas are characterized by tumour suppressor gene mutations and chromosomal instability, serrated adenomas...

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